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Pharmaceutical Analysis: GPAT preparation


Pharmaceutical Analysis is one of the interesting subjects in Pharmacy. Knowing how the analysis of compounds is carried out and what actually happens at molecular levels is really interesting. 
The answers of questions like 'what happens at molecular levels?', 'What exactly happens when a compound is exposed to various radiations/chemicals during analysis?' are given in the principles of every analytical tool. 
Mainly, we need to focus on the principles of analytical methods while preparing for GPAT.

Important points you need to focus on while preparing for Pharmaceutical Analysis:

 (Click on the following topics to read article)

1. Principles (In detail), Instrumentation (parts of the instruments and their role) and applications of --
2. In NMR studies, focus on chemical shift point (principle), shielding, deshielding phenomenon, coupling constant.

3. Chromatography is a vast yet very interesting topic to study. It includes, paper chromatography, Thin Layer Chromatography (TLC), High Performance Thin Layer Chromatography (HPTLC), Column Chromatography, High Performance Liquid Chromatography (HPLC) and Gas Chromatography.

In all these chromatographic techniques, you need to focus on--
  • Paper Chromatography- Types of papers, solvent system, limitations.
  • TLC & HPTLC- types of stationary phases, properties and limitations of each type of stationary phase, preparation of plates, limitations and applications.
  • Column chromatography- principle, types of columns, solvent system, stationary phases.
  • Gas chromatography- principle, types of columns, detectors.
  • HPLC-  types of columns, types of stationary phases, solvent system, instrumentation.
4. Know the difference between normal phase and reverse phase chromatography. Likewise the use of polar and non-polar solvents.

5. Differentiate chromatographic techniques based on their qualitative and quantitative applications.

6. Know the difference between spectroscopy and spectrometry.

7. Remember the wavelength ranges of radiations in respective studies. 

That's what I feel important for GPAT exams.
😊

Let's start studying!
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