GPAT 360

Evaluation of tablets   Notes on tablets II Tablets are evaluated for their physical, chemical and bioavailability properties. Stability testing is also an important evaluation parameter. Theset are divided into official and unofficial tests. Unofficial tests : 1. Appearance 2. Size and shape 3. Organoleptic properties (color, odor, taste) 4. Hardness 5. Friability Official tests : 1. Drug content 2. Weight variation 3. Disintegration 4. Dissolution Let's see important parameters in all the test (from GPAT point of view): Measurement of crown thickness : Instruments used are Micrometer and Caliper scale . Tablet thickness values variations: ±5% variation of a std value. Instruments used for color evaluation : Reflectance spectrophotometry Tristimulus colorimetric measurements Microreflectance photometer (measure the color uniformity and gloss on a tablet surface) Hardness and Friability Hardness : tablet crushing str

    Short notes on tablets I In this first article on tablets I am going to provide some important points regarding tablet formulation.   ü   I : Advantages, disadvantages, tablet defects and the excipients used in the formulation of tablets ü   II : Evaluationparameters and types & classes of tablets . Second part of this topic will be provided in the next post. So, for short notes on second point please refer the next post. Let’s start with the first point in this topic. ADVANTAGES OF TABLETS Oral route of administration is the most preferred route for the administration of drugs for their systemic effects. Tablets are mostly preferred for this due to following advantages: ·          Unit dosage forms ·          Greatest dose precision ·          Least content variability ·          Lowest cost ·          The lightest and the most compact oral dosage forms ·          Easy transportation as compared to liquids ·          Product identification is easy

GPAT PREPARATION TIPS   In order to prepare for GPAT examination, selection of right amount of study material and smart work with time management is important. Some GPAT aspirants start preparing for GPAT exam before 3-4 months of date of the exam. In this case short notes and study tricks come in handy. You need to prepare short trick notes to remember concepts and lengthy matter efficiently. Time management is crucial while preparing for exam. You need to find proper reference material, previous year question papers in order to prepare short notes and diagrammatic illustrations for study. Use of diagrammatic illustrations and mnemonics will be beneficial while studying pharmacology. Short charts and tree diagrams will also be helpful. E.g. types of vitamins, their role and vitamin deficiencies. When you try to link information with a diagram or an illustration it will be easier to remember other important topics associated with it. E.g. While studying Respiratory syste